Oxidation of Glyoxylic Acid to Oxalic Acid by Glycolic Acid Oxidase

Glyoxylic acid oxidation by rat liver.

The enzymatic formation of glyoxylate from tricarboxylic acids has focused attention on this cu-keto acid as a possible intermediate of alternate metabolic pathways (l-3). Although the isocitritase reaction has not been shown in animal tissues, recent work has indicated that the principal degradative pathway for glycine by rat liver preparations proceeds via glyoxylic acid (4). Although the oxi...

Oxidation and reduction of glycolic and glyoxylic acids in plants. II. Glyoxylic acid reductase.

Clagett, Tolbert, and Burris (1) discovered an enzyme of wide-spread occurrence in the green parts of many plants which catalyzes the oxidation of glycolic and L-lactic acids. The enzyme, which was partially purified from tobacco leaves, seemed to catalyze the oxidation of glycolic acid, through glyoxylic acid, to formic acid and CO, (2). In view of the possible importance of glycolic acid oxid...

A Novel Microbial Aldehyde Oxidase Applicable to Production of Useful Raw Materials, Glycolic Acid and Glyoxylic Acid, from Ethylene Glycol

Glycolic acid is an attractive raw material which is used as a dyeing and tanning agent in the textile industry, a flavoring agent and preservative in the food processing industry, and a skin care agent in the pharmaceutical industry. It is also utilized for the production of polyglycolic acid and other biocompatible copolymers. Glycolic acid can be isolated from natural sources, such as sugarc...

Activation of glycolic acid oxidase in plants.

The enzyme which oxidizes glycolic acid to glyoxylic acid is present in sufficient concentrations to support active respiration in a wide variety of plants (1). Glycolic acid itself is present in plants in small amounts (2), and, as yet, it has been the only 2-carbon organic acid which has been found to accumulate Cl4 during short time photosynthesis experiments with Cl402 (3). Thus both the fr...

Oxalic acid